Home Chemistry Heterocyclic Building Blocks Tetrahydrofurans 2-Oxabicyclo[2.1.1]Hexane
Ring Opening Reactions: Due to the strain in the three-membered oxirane ring, 2-oxabicyclo[2.1.1]hexane can undergo ring-opening reactions under appropriate conditions. For example, it can be hydrolyzed in the presence of an acid or a base to produce a diol.
Oxidation Reactions: Like other organic compounds, 2-oxabicyclo[2.1.1]hexane can undergo oxidation reactions. Oxidants like potassium permanganate (KMnO4) or hydrogen peroxide (H2O2) can be used to oxidize it, depending on the desired products.
Substitution Reactions: The oxygen atom in the oxirane ring can undergo nucleophilic substitution reactions. For instance, if you react 2-oxabicyclo[2.1.1]hexane with a strong nucleophile, it can undergo ring-opening and substitution to form new compounds.
Reduction Reactions: 2-oxabicyclo[2.1.1]hexane can be reduced using reducing agents like lithium aluminum hydride (LiAlH4) or sodium borohydride (NaBH4) to form saturated derivatives.
Addition Reactions: Depending on the conditions and reagents used, 2-oxabicyclo[2.1.1]hexane can undergo addition reactions. For example, it can undergo electrophilic addition reactions with suitable reagents.
Catalytic Reactions: Certain catalytic processes, such as catalytic hydrogenation or catalytic oxidation, may be employed to modify the structure of 2-oxabicyclo[2.1.1]hexane.
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(4-Cyano-2-oxabicyclo[2.1.1]hexan-1-yl)methyl acetate
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1-(Hydroxymethyl)-2-oxabicyclo[2.1.1]hexane-4-carbonitrile
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1-(Aminomethyl)-2-oxabicyclo[2.1.1]hexane-4-carbonitrile
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1-(Iodomethyl)-2-oxabicyclo[2.1.1]hexane-4-carbonitrile
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(2-Oxabicyclo[2.1.1]hexan-1-yl)methyl acetate
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2-Oxabicyclo[2.1.1]hexane-4-carboxylic acid
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